METHOD FOR STERILIZING BLOOD PLASMA AND BLOOD PLASMA PREPARATIONS Russian patent published in 2002 - IPC

FIELD: medicine. SUBSTANCE: method involves freezing blood plasma samples or blood plasma preparations, treating them with gamma-radiation at a dose of 40-50 kGr and then defrosting the samples. The blood preparation samples are frosted at 0.2-2.0 C/min rate until temperature of minus 60-196 C is reached. Gamma-radiation treatment is carried out step-by-step making pauses between radiation steps. Defrosting is carried out at 20-30 C/min rate until temperature of plus 5-10 C is reached. Plasma samples plasma preparation samples are optionally subjected to ultrasonic radiation treatment at known frequency so that specific absorbed energy is equal to 10³ to 10⁶ kJ/kg. EFFECT: fully inactivated viral and other microbial agents; retained plasma preparation quality. 2 cl, 1 dwg, 9 tbl