CYANOGUANIDINES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL PREPARATION BASED ON THEREOF Russian patent published in 2002 - IPC

Abstract RU 2195451 C2

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to novel guanidines of the formula (I): where addition to pyridine ring is carried out at 3 or 4 position; R means one or more substitutes that can be similar or different and taken among group consisting of hydrogen, halogen atom or alkoxy-group; X means a single bond, substituted C₃-C₇-cycloalkylene, arylene, one or two sulfur atoms; Q₁ and Q₂ mean C₁-C₁₀-bivalent linear or branched hydrocarbon radical. Compounds of the formula (I) inhibit unfavorable cells proliferation and can be used in medicine. EFFECT: improved methods of synthesis, valuable medicinal properties of compounds. 9 cl, 2 tbl, 19 ex

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RU 2 195 451 C2

Authors

Petersen Khans Jorgen

Khunnekhe Sharlotte Skou

Dates

2002-12-27—Published

1998-05-15—Filed