CYANOGUANIDINES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL PREPARATION BASED ON THEREOF Russian patent published in 2002 - IPC

Abstract RU 2194697 C2

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to novel cyanoguanidines of the formula (I) where joining to pyridine ring is performed at 3 or 4 position; R means one or more substitutes that are taken among group comprising of hydrogen atom, C₁-C₄-alkyl or alkoxy-group; Q means linear saturated bivalent hydrocarbon C₅-C₁₄-radical; X means carboxy-, amino-, tetrahydropyranyl-hydroxy-group, C₁-C₄-saturated or unsaturated alkoxycarbonylamino-, alkoxycarbonyl- or di-(alkoxy)- phosphinoylhydroxy-group. Compounds of the formula (I) inhibit undesirable cell proliferation and can be used in medicine. EFFECT: improved method of synthesis, valuable medicinal properties. 8 cl, 2 tbl, 22 ex _

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RU 2 194 697 C2

Authors

Khunnekhe Sharlotte Skou

Ottosen Ehrik Rjutter

Dates

2002-12-20—Published

1998-05-15—Filed