FIELD: medicine, toxicology, pharmacology, radiobiology. SUBSTANCE: invention is designated for determination of effective doses of toxic and drugs. Testing is carried out in test-objects for three stages. In the first stage range of doses is determined at which abrupt transition of effects from 0 to 1 occur. The second stage involves reproduction of the following sequences of effects by increasing or decreasing the dose in required range by 1.1-fold: 00-0001-11; 00-0010-11; 00-0011-11; 00-0100-11; 00-0101-11; 00-0110-11; 00-0111-11; 00-1000-11; 00-1001-11; 00-1010-11; 00-1011-11; 00-1100-11; 00-1101-11; 00-1110-11 being increasing a number six of test-objects. In the third stage additional tests in special required points are carried out and efficiency function is built by method of nuclear estimation of regression and effective doses are determined. EFFECT: enhanced precision of method. 3 tbl, 2 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREDICTING AN INCREASED RISK OF A COMPLICATED COURSE OF THE EARLY POSTOPERATIVE PERIOD IN PATIENTS WITH ISCHEMIC CARDIOMYOPATHY AT THE PREOPERATIVE STAGE | 2022 |
|
RU2801159C1 |
| ALLOCATION OF MACHINE LEARNING RESOURCE | 2013 |
|
RU2648573C2 |
| METHOD FOR DETERMINING HOT LONG-TERM HARDNESS OF HEAT-RESISTANT STEEL | 2022 |
|
RU2810481C1 |
| METHOD FOR ASSESSMENT OF FIRING EFFICIENCY OF COMBAT REMOTE CONTROLLED MODULE LOCATED ON MOBILE OBJECT | 2015 |
|
RU2604909C9 |
| METHOD TO DETERMINE CONCENTRATIONS OF BIOLOGICAL TISSUE CHROMOPHORES | 2012 |
|
RU2506567C1 |
| METHOD FOR PREDICTION OF RISK OF UNFAVOURABLE OUTCOME IN PATIENTS WITH ACUTE CORONARY SYNDROME AND CONCOMITANT TYPE 2 DIABETES MELLITUS | 2014 |
|
RU2573499C1 |
| ADVERTISEMENT PORTFOLIO MODEL, COMPLEX SYSTEM FOR CONTROLLING ADVERTISEMENT RISK USING SAID ADVERTISEMENT PORTFOLIO MODEL, AND METHOD FOR TAKING AN INVEST DECISION WITH USE OF ADVERTISEMENT PORTFOLIO | 2000 |
|
RU2233479C2 |
| DEVICE FOR MEASURING HAEMOGLOBIN CONCENTRATION AND DEGREE OF BLOOD OXYGENATION IN MUCOUS MEMBRANES | 2013 |
|
RU2528087C1 |
| METHOD FOR PREDICTION OF COMPLICATIONS FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY | 2013 |
|
RU2536279C1 |
| METHOD FOR DETERMINING THE COORDINATES OF A RADIO EMITTING OBJECT IN THE WORKING AREA OF A MULTIPOSITIONAL PASSIVE RADIO ENGINEERING COMPLEX AND APPARATUS FOR IMPLEMENTATION THEREOF | 2020 |
|
RU2757197C1 |
