METHOD OF PREDICTING AN INCREASED RISK OF A COMPLICATED COURSE OF THE EARLY POSTOPERATIVE PERIOD IN PATIENTS WITH ISCHEMIC CARDIOMYOPATHY AT THE PREOPERATIVE STAGE Russian patent published in 2023 - IPC A61B6/00 A61B8/00 

FIELD: medicine, radionuclide diagnostics in cardiology.

SUBSTANCE: invention can be used to predict the development of a complicated course of the early postoperative period in patients with ischemic cardiomyopathy at the preoperative stage. Echocardiography (EchoCG) is performed and the final systolic volume of the left ventricle (LV systolic volume) is determined. Radionuclide equilibrium ventriculography with 99mTc-pyrophosphate is conducted at rest and against the backdrop of successive intravenous infusions of dobutamine at doses of 5, 10, 15 mcg/kg/min for 5 minutes for each dose. LV Entropy is determined at rest and LV Entropy is determined at the peak of the stress test. The prognostic probability of developing a complicated course of the early postoperative period in patients with ischemic cardiomyopathy (P) is calculated using the following formula: Р=1/(1+e^{(-(-7.64+2.82*Х-0.23× Y+0.03*Z))} where X is equal to 1 if the patient has an operation on the mitral valve, equals to 0 if the patient does not have an operation on the mitral valve; Y is LV ΔEntropy calculated by the formulaΔ LV Entropy = (LV Entropy at peak stress test - LV Entropy at rest); Z is LV CSR. If the P value is greater than 0.5, the development of complications in the early postoperative period after surgical treatment of ischemic cardiomyopathy is predicted.

EFFECT: method enables to select the patients with an increased risk of developing cardiovascular complications in the early postoperative period due to echocardiographic and radionuclide signs.

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