COMPOUNDS WITH AFFINITY AND SELECTIVITY SIMILAR TO CHELATE-FORMATION WITH ELEMENTS OF THE FIRST TRANSIENT ROW AND THEIR APPLICATION IN THERAPY AND DIAGNOSTICS Russian patent published in 2003 - IPC

FIELD: medicine. SUBSTANCE: it is described the method to inhibit the growth of bacterial and fungous cells either at the surface or in solution including complex-former of formula 1: , where p, q, r, R1, R2, R3 and R4 have values presented in the formula of innovation, moreover, molecular weight of the mentioned complex-former does nor exceed 2000 at affinity and selectivity of chelate-formation being with elements of the first transient row. Introduction of free or bound compound or physiological salts of free or bound compound leads to lower biological availability of the first transient row elements in vivo and/or removal of elements with similar chemical properties out of the bodies of the first transient row elements. These characteristics make such compounds to be applied in treating diseases associated with body excess of the first transient row elements and those with similar chemical properties. This innovation demonstrates the fact that these compounds inhibit division of mammalian, bacterial and fungous cells and, thus, could be applied in treating tumor, infectious, inflammatory diseases, immune response and for pregnancy discontinuity. These compounds are able to decrease biological tissue availability in vivo, and they are used in treating tissue lesions mediated by free radicals, and tissue lesions mediated by oxidative processes. At combination, before introduction into complex with cations of the first transient row elements of radioactive or paramagnetic properties or elements of chemical properties similar to those in the first transient row elements, the obtained complexes could be applied as diagnostic means in the field of nuclear medicine and nuclear magnetic resonance visualization. EFFECT: higher efficiency. 47 cl, 7 ex