FIELD: pharmacy. SUBSTANCE: invention relates to novel crystalline γ--modification of p-butylaminobenzoic acid 2-dimethylaminoethyl ester hydrochloride as topical anesthetic agent and method for its preparing. Method of synthesis involves heating to boiling point solution of p-butylaminobenzoic acid 2-dimethylamino- ethyl ester hydrochloride in water, organic solvent or in their mixture followed by its dispersing into cooling agent and sublimating drying. The novel crystalline γ--modification of p-butylaminobenzoic acid 2- dimethylaminoethyl ester hydrochloride represents white crystalline powder, easily soluble in water and 95-96% ethanol and moderately soluble in chloroform, its melting point is 149.5 γ- 0.4 C. EFFECT: improved preparing method. 2 cl, 5 tbl, 3 dwg
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