FIELD: organic chemistry, biochemistry, medicine. SUBSTANCE: invention relates to heterocyclic compounds N-oxides of the formula (I) where R1 represents CH3, CH2F, CHF2, CF3; R2 represents CH3, CF3; R3 represents F, Cl, Br, CH3; R4 represents H, F, Cl, Br, CH3. Invention can be used as a therapeutic agent for treatment of patients with asthma, eosinophilia, neutrophilia, chronic bronchitis, pulmonary chronic disease and chronic obstructive disease of respiratory ways. EFFECT: valuable medicinal properties of compounds. 6 cl, 1 dwg, 2 tbl
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Authors
Dates
2003-06-10—Published
1999-11-02—Filed