TEST SYSTEM FOR DETECTING ANTIBODIES TO HBS ANTIGEN AND TEST SYSTEM BLOCKER Russian patent published in 2003 - IPC

FIELD: medicine. SUBSTANCE: method involves using test system having stripped palette sensibilized with recombinant yeast HbsAg of ay and/or ad serologic types, rinsing solution, biotin HbsAg conjugate, avidine-pyroxidase or streptavidine-peroxydase, substrate buffer with hydrogen peroxide, chromogen, stop-reagent, sample of positive and negative control as blood serum obtained by immunizing healthy donors with recombinant yeast vaccine against hepatitis B, titrated according to international standard of anti-Hbs contents or branch standard sample of human immunoglobulin against hepatitis B, blocker in the form of 5% sodium caseinate solution in sodium-borate buffer having pH equal to 8.3, reference-standard for quantitatively determining antibodies to HBs-antigen as blood serum produced by immunizing healthy donors with recombinant yeast vaccine against hepatitis B, titrated according to international standard of anti-Hbs contents or branch standard sample of human immunoglobulin against hepatitis B and logarithm table for calculating quantitative contents of antibodies to HBs-antigen. EFFECT: high specificity and safety of analysis. 2 cl, 1 dwg, 4 tbl