FIELD: medicine, biochemistry, pharmacy. SUBSTANCE: invention proposes inhibitor of Rho-kinase as the novel pharmaceutical agent, in part, as therapeutic agent used in hypertension, stenocardia, as suppressive agent in cerebrovascular contraction, as therapeutic agent in asthma, disturbance of peripheral circulation, arteriosclerosis, as an anticancer medicinal agent, as therapeutic agent in osteoporosis, therapeutic agent in retinopathy. Except for, inhibitor of Rho-kinase is used as reagent and diagnostic agent. EFFECT: expanded assortment of medicinal agents. 11 cl, 10 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | 2008 |
|
RU2453532C2 |
| WATER-BASED LIQUID COMPOSITION CONTAINING AMIDE COMPOUND | 2007 |
|
RU2476219C2 |
| COMBINED THERAPY INCLUDING SGLT INHIBITORS AND DPP4 INHIBITORS | 2009 |
|
RU2481106C2 |
| PIPERAZINE COMPOUND, INHIBITOR OF PRODUCTION OF TNF (TUMOR NECROSIS FACTOR)-α AND/OR PROMOTER OF INDUCTION OF IL-10 (INTERLEUKIN-10) AND AGENT FOR PROPHYLAXIS OR TREATMENT BASED ON THEREOF | 1998 |
|
RU2199534C2 |
| COMPOSITIONS FOR TREATING AND PREVENTING VASOMOTOR SYMPTOMS | 2017 |
|
RU2768875C2 |
| THIOMORPHOLINE COMPOUND AND METHOD FOR MAKING THEREOF | 2006 |
|
RU2379305C2 |
| CONDENSED THIOPHENE DERIVATIVE, BENZOTHIOPHENE DERIVATIVE, THIENOBENZOXAZEPINONE DERIVATIVE, PHARMACEUTICAL AGENT AND PHARMACEUTICAL COMPOSITION | 1998 |
|
RU2197491C2 |
| OXIME DERIVATIVES AND PREPARATION THEREOF | 2006 |
|
RU2420525C2 |
| NEW ANTITHROMBOTIC AGENT | 2010 |
|
RU2570426C2 |
| PREVENTIVE OR THERAPEUTIC REMEDY FOR PHOTODERMATOSIS | 2021 |
|
RU2812785C1 |
