DERIVATIVES OF CAPUROMYCINN ELICITING ANTIBACTERIAL ACTIVITY, PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF, METHOD OF TREATMENT OF INFECTIOUS DISEASES, MICROORGANISM ABLE TO PRODUCE ABOVE MENTIONED DERIVATIVES AND METHOD FOR PREPARING SUCH DERIVATIVES USING THIS MICROORGANISM Russian patent published in 2003 - IPC

FIELD: organic chemistry, biotechnology, antibiotics, microbiology, pharmacy. SUBSTANCE: invention relates to derivatives of capuromycin and their pharmaceutically acceptable salts of the general formula (I): where R¹ means methyl group; R² means methyl group; R⁴ means hydroxy-group; X means methylene group; or R¹ means methyl group; R² means hydrogen atom; R⁴ means hydroxy-group; X means methylene group; or R¹ means methyl group; R² means methyl group; R⁴ means hydrogen atom; X means methylene group; or R¹ means hydrogen atom; R² means hydrogen atom; R⁴ means hydroxy-group; X means methylene group; or R¹ means methyl group; R² means methyl group; R⁴ means hydroxy-group; X means sulfur atom. Invention elates also to pharmaceutical composition based on compounds of the formula (I), method of treatment of patients with infectious diseases, microorganism able to produce above indicated derivatives and method for preparing such derivatives using this microorganism. Invention provides preparing novel compounds exhibiting an antibacterial effect. EFFECT: improved preparing and treatment methods, valuable medicinal properties of compounds. 48 cl, 7 tbl, 56 ex