METHOD FOR MANUFACTURING CARCASSLESS BIOLOGICAL PROSTHESIS OF CARDIAC AORTIC VALVE Russian patent published in 2003 - IPC

FIELD: medical engineering. SUBSTANCE: method involves selecting aortic xenocomplexes from pig hearts, their washing, preparing and treating aorta root, forming carcassless valve prosthesis with Valsalva sinuses being retained. In-plane muscle resection is carried out on the right coronary cusp and anterior mitral valve cusp with an area of greater than 1.0 mm thickness and 1-1.5 mm width being retained. Flexible cuff is formed from pretreated calf pericardium tissue in tributary part of the prosthesis with muscular sites and fibrous ring getting closed. It is attached to the internal aorta wall on one side below the level of cusps attachment with continuous blanket suture capturing intima and median portion only; and it is attached to the external aorta wall with adventitial and median portion being captured without aorta intima being caught into the suture. Then, the aortic valve prostheses are sterilized in epoxy-compound solution and preserved. EFFECT: reduced risk of complications at the places the valves and blood vessels join each other; improved functional properties; reduced trans-valve gradient and calcinosis values.