DERIVATIVES OF CARBAPENEM, THEIR USING AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARING Russian patent published in 2004 - IPC

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to derivative of carbapenem of the formula (I): wherein R¹ represents a modifying group that is hydrolyzed in living body; R² and R³ are similar or different and each represents lower alkyl; R represents group of the formula (B): or the formula (C): wherein R⁴ and R⁵ are similar or different and each represents hydrogen atom or lower alkyl; R⁶ represents alkyl with 1-10 carbon atoms. Invention relates also to an antibacterial agent comprising derivatives of carbapenem and derivative of carbapenem of the general formula (II): wherein values R, R², R³ are given above; R⁷ is hydrogen atom or protecting group for carboxyl group, or to its sodium salt. EFFECT: improved preparing method. 10 cl, 2 tbl