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2 215 294

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IPC

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Application

2001128465/14, 2001-10-23

(24)

Start date

2001-10-23

(22)

Actual filing date

2001-10-23

(45)

Published

2003-10-27

(72)

Inventor

Batalova T.N.Guzova V.A.Kozlov L.V.Maslova Ju.Ju.Aleshkin V.A.Panurina R.L.

(73)

Holder

Gosudarstvennoe Uchrezhdenie Moskovskij Nauchno-Issledovatel'Skij Institut Ehpidemiologii I Mikrobiologii Im. G.N. Gabrichevskogo

METHOD FOR PREPARING MONOSPECIFIC POLYCLONAL ANTISERA TO ANTIGEN-RELATED PROTEINS Russian patent published in 2003 - IPC

Abstract RU 2215294 C2

FIELD: medicine, immunology. SUBSTANCE: method involves immunization of animal by a single muptipoint intracutaneous administration of immunochemically pure protein-antigen in back region in the dose 100-500 mcg per animal in the presence of three volumes of complete Freund's adjuvant relatively to protein-antigen solution. Then method involves animal blood sampling in 2 months after immunization and for 6 months, preparing immune serum and its selective adsorption with other antigen-related proteins. Invention can be used for preparing monospecific polyclonal antisera to closely related proteins in diagnosis of some diseases. Invention provides the development of simplified, relatively inexpensive and technological method for preparing monospecific polyclonal antisera to antigen-related proteins. EFFECT: improved preparing method. 1 ex

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RU 2 215 294 C2

Authors

Batalova T.N.

Guzova V.A.

Kozlov L.V.

Maslova Ju.Ju.

Aleshkin V.A.

Panurina R.L.

Dates

2003-10-27—Published

2001-10-23—Filed