FIELD: medicine, microbiology. SUBSTANCE: lyophilized lactobacilli culture is covered by envelope that comprises polyvinylpyrrolidone tanned with tannic acid. As result of technological process forming aggregates of film-forming agent macromolecules occurs. Method provides the enhanced viability of microorganisms in the course of technological process due to using components that are safety for the host and microorganisms. Micro- capsulated lactobacilli can be placed then to different medicinal forms and used in complex with other preparations. EFFECT: improved preparing method. 1 tbl
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