LOCAL APPLICATION OF ANTIANDROGEN AGAINST HAIR FALL OUT AND OTHER HYPERANDROGENIC STATES Russian patent published in 2004 - IPC

Abstract RU 2225390 C2

FIELD: organic chemistry, cosmetology. SUBSTANCE: the present innovation deals with new compounds of 2-hydroxy-2 methyl- N-(4-X-3- (trifluoromethyl)phenyl)-3- perfluoracylamino)propionamide, where X means nitro, cyano or halogen, and perfluoracylamino contains 2-3 carbon atoms and 0-1 hydrogen atom. The mentioned compounds specifically inhibit and/or eliminate receptors of head skin androgens and, thus, could be applied as cosmetic substance in case of cutaneous disorders caused by excess of androgens, such as hair fall out, hirsutism, acne and androgenic alopecia. EFFECT: higher efficiency of application. 11 cl, 11 ex, 4 tbl

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RU 2 225 390 C2

Authors

Sovak Milos

Seligson Allen L.

Kehmpion Brajan

Braun Dzhehjson V.

Dates

2004-03-10Published

2000-05-25Filed