ASN-BOKERIYA-BOLDYREV CARDIOPLEGIC SOLUTION Russian patent published in 2011 - IPC A61K9/08 A61K31/195 A61K33/14 A61P9/00 

Abstract RU 2413502 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, namely to cargiosurgery, and represents a cardioplegic solution containing sodium chloride, potassium chloride, magnesium chloride, calcium chloride, L-carnosine, N-acetylcarnosine, water for injections differing by the fact that the solution in addition contains mannitol and L-histidine components of which are taken in a certain ratio.

EFFECT: invention provides higher buffer capacity and decreased osmolarity of the cardioplegic solution with physiological parametres pH that leads to effective cardiac resuscitation and higher restoration of warm activity and high myocardial contractility after oxidation process.

1 ex, 4 tbl

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Authors

Bokerija Leo Antonovich

Boldyrev Aleksandr Aleksandrovich

Movsesjan Ruben Rudol'Fovich

Alikhanov Sardar Amurkhanovich

Arzumanjan Elena Sergeevna

Dates

2011-03-10Published

2009-07-24Filed