FIELD: organic chemistry, biochemistry, pharmacy.
SUBSTANCE: invention relates to derivatives of sulfonamides of the formula (Ia):
wherein R means -CH(R2)Ar'; Ar1 means phenyl or naphthyl ring that can be substituted. Compounds are inhibitors of proteinase C of procollagen. Invention describes also a pharmaceutical composition based on compounds of the formula (Ia).
EFFECT: valuable biochemical properties of compounds.
29 cl, 2 tbl, 22 ex
| Title | Year | Author | Number |
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| DERIVATIVES OF ARYLSULFONYLAMINOHYDROXAMIC ACID, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF INHIBITION OF MATRIX METALLOPROTEINASES AND METHOD OF PATIENT TREATMENT | 1996 |
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| METHODS FOR EPLERENONE OBTAINMENT | 2003 |
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