METHOD FOR OBTAINING AQUEOUS SOLUTION FOR INFUSIONS Russian patent published in 2004 - IPC

FIELD: pharmaceutics, clinical medicine, chemico-pharmaceutical industry.

SUBSTANCE: the suggested method deals with preparing polyvinyl pyrrolidone solution followed by its purification, dissolving all components, sterilization of ready-to-use product and bottling. Moreover, one should pre-dissolve polyvinyl pyrrolidone in water at 20-35 C and laminar mixing for 20-30 min, then obtained solution should be supplemented with mineral salts and nonpyrogenic activated coal to keep the obtained solution with coal at pH being 5.6-6.0 and at 100-102 C at laminar mixing for 25-30 min, then solution should be cooled up to 20-30 C, then comes filtration of solution to remove coal at a filter with coal alluvium to perform, finally, pH correction up to 6.1-6.5. The innovation provides improved PVP properties due to purifying it against admixtures, obtains practically colorless and stable PVP preparation both at manufacturing moment and during storage period.

EFFECT: higher efficiency.

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