7-ACYLAMINOCEPHALOSPORINS SUBSTITUTED IN POSITION 3 WITH CYCLIC AMINOGUANIDINE GROUPS Russian patent published in 2005 - IPC

FIELD: organic synthesis.

SUBSTANCE: invention provides substituted 7-acylaminocephalosporins of formula I:

(I), where W denotes CH or B; V denotes NO; R₁ hydrogen or С₁-С₄-alkyl; R₃ hydrogen or ester residue; and R₂ one of the following groups: , , , , in which X, R₅, R₆, R'₆, R₇, and Hal have meanings indicated in claims, in free state, in the form of salts and/or solvates, or, if such forms are stable, in the form of internal salt, quaternary salt, or their hydrates, possessing antimicrobial activity. Invention also discloses a method for preparing such compounds and a pharmaceutical connected containing them.

EFFECT: increased choice of antimicrobial preparations.

13 cl, 10 tbl, 225 ex