FIELD: organic chemistry, heterocyclic compounds, purines, medicine.
SUBSTANCE: invention relates to a method for treatment of arrhythmia in mammal. Method involves administration of agonist of adenosine A1-receptors in the therapeutically effective minimal dose of the formula:
wherein R1 represents optionally substituted heterocyclic group. The indicated dose of agonist is in the range from 0.0003 to 0.009 mg/kg. Method shows the enhanced effectiveness and doesn't result to undesirable adverse effects.
EFFECT: improved treatment method, valuable medicinal properties of substances.
11 cl, 1 dwg, 2 ex
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Authors
Dates
2005-03-20—Published
2001-09-07—Filed