METHODS AND COMPOSITIONS IMPROVING PATIENT'S TOLERANCE OF MYOCARDIAL VISUALISATION TECHNIQUE Russian patent published in 2012 - IPC A61K31/7076 A61K31/52 A61K49/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: given invention refers to a pharmaceutical composition improving patient's tolerance of myocardial visualisation techniques and containing caffeine, regadenoson, and at least one pharmaceutical excipient, and to using said composition wherein caffeine is introduced in the patient in a combination with regadenoson, before the introduction of regadenoson or in the form of one pharmaceutical composition. The invention also refers to using caffeine, radionuclide and regadenoson for improving patient's tolerance of vasodilator-induced stress myocardial perfusion visualisation in an individual wherein the myocardium is examined by determining areas of blood flow insufficiency after the introduction of radionuclide and regadenoson. The invention also refers to the single intravenous bolus dosing of caffeine and regadenoson for improving patient's tolerance of vasodilator-induced stress myocardial perfusion visualisation in an individual.

EFFECT: creating a pharmaceutical composition improving patient's tolerance of myocardial visualisation.

22 cl, 5 dwg, 2 tbl, 2 ex