METHOD FOR PRODUCTION OF BIVALANT VACCINE FOR PROPHYLAXIS OF MENINGOCOCCUS INFECTION Russian patent published in 2005 - IPC

Abstract RU 2250113 C2

FIELD: biotechnology.

SUBSTANCE: claimed method includes conjugation of capsule polysaccharides A and C with synthesized peptide outer membrane protein fragments of meningococcus of serogroup B, having frank protective activity against to meningococcus serogroups A, B and C. capsule polysaccharides of meningococcus serogroups A and C are used in preparation of bivalent vaccine B/A and B/C, respectively. Said polysaccharide are oxidized before conjugation.

EFFECT: vaccine with improver protective activity against to meningococcus infection of various serogroups.

3 cl, 1 tbl, 7 dwg

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RU 2 250 113 C2

Authors

Nesmejanov V.A.

Kotel'Nikova O.V.

Vol'Pina O.M.

Feoktistov K.M.

Chibiskova O.V.

Zhmak M.N.

Koroev D.O.

Alliluev A.P.

Ivanov V.T.

Dates

2005-04-20Published

2003-06-04Filed