FIELD: organic chemistry, biochemistry, medicine, pharmacy.
SUBSTANCE: invention relates to N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazole carboxamide of the formula: and to its pharmaceutically acceptable salts. Also, invention describes a pharmaceutical composition inhibiting activity of protein-tyrosine kinases and comprising the indicated compound, a method for treatment of disorders associated with protein-tyrosine kinases, such as an immune disorder, and oncology disease, and a method for cancer treatment.
EFFECT: valuable biochemical and medicinal properties of compounds and composition.
5 cl, 2 tbl, 581 ex
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Authors
Dates
2005-09-20—Published
2000-04-12—Filed