FIELD: medicine, vaccines.
SUBSTANCE: invention relates to a method for producing the combined vaccine comprising antigens of diphtheria, tetanus, whooping cough and hepatitis B. method involves stages of independent adsorption of each protective antigen on aluminum hydroxide used as a gel-adsorbent to different antigens: diphtheria, tetanus, whooping cough and hepatitis B followed by mixing adsorbed antigens. Advantage of invention involves the development of a method providing the improved evaluation and prophylaxis of adverse effect.
EFFECT: improved producing method.
11 cl, 3 dwg, 1 tbl, 10 ex
| Title | Year | Author | Number |
|---|---|---|---|
| MIXED VACCINE FOR IMMUNE PROPHYLAXIS OF VIRAL HEPATITIS B, TETANUS, DIPHTHERIA AND WHOOPING COUGH | 1998 |
|
RU2130778C1 |
| COMBINED VACCINE TO PREVENT WHOOPING COUGH, DIPHTHERIA, TETANUS, HEPATITIS AND INFECTIONS CAUSED BY TYPE B HAEMOPHILUS INFLUENZAE | 2015 |
|
RU2626532C2 |
| COMBINED HEPTAVALENT VACCINE | 2012 |
|
RU2705163C2 |
| MIXED VACCINE FOR IMMUNOPROPHYLAXIS OF WHOOPING COUGH, DIPHTHERIA, TETANUS AND VIRAL HEPATITIS B AND D | 2003 |
|
RU2233673C1 |
| MIXED VACCINE FOR IMMUNE PROPHYLAXIS OF VIRAL HEPATITIS B, TETANUS AND DIPHTHERIA | 1998 |
|
RU2130779C1 |
| THE MIXED VACCINE, A METHOD OF SIMULTANEOUS MIXED VACCINATION AND A METHOD OF IMMUNOGENICITY INCREASE | 1993 |
|
RU2121365C1 |
| PREPARATION OF VACCINES CONTAINING HEPATITIS TYPE B VIRUS SURFACE ANTIGEN AND SURFACE-ACTIVE MATERIAL | 2006 |
|
RU2444374C2 |
| COMBINED VACCINE FOR PREVENTING PERTUSSIS, DIPHTHERIA, TETANUS | 2015 |
|
RU2596919C2 |
| POLYVALENT ASSOCIATED DIPHTHERIA, TETANUS TOXOIDS AND PERTUSSIS POLIOVIRUS VACCINES | 1997 |
|
RU2194531C2 |
| MULTIPLE VACCINATION INCLUDING SEROGROUP C MENINGOCOCCI | 2006 |
|
RU2457858C2 |
