FIELD: biotechnology, amino acids, microbiology.
SUBSTANCE: invention relates to a method for preparing L-lysine by fermentation of corynebacteria with separated or combined enhanced nucleotide sequences of genes encoding biosynthesis of L-lysine. Corynebacteria carry mutations MC20 or MA16 in promoter of gene dapA and the enhanced gene lysE. Invention provides producing L-lysine with the enhanced effectiveness degree.
EFFECT: improved producing method.
8 cl, 3 dwg, 2 tbl, 15 ex
Authors
Dates
2005-11-20—Published
2000-07-07—Filed