FIELD: biotechnology.
SUBSTANCE: the suggested method deals with growing Salmonella typhimurium culture, washing with sterile 0.9%-NaCl solution (pH 7.0), treating with 10%-aqueous ammonia solution up to final concentration of 1% and incubating the mixture obtained for 5 h, then centrifuging takes place of salmonella suspension, then one should pour out supernatant to resuspend the residue with sterile 0.9%-NaCl solution (pH 7.0). The innovation suggested enables to obtain inactivated Salmonella typhimurium culture that causes no lethality at subcutaneous injection in mice.
EFFECT: higher efficiency of inactivation.
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCTION OF VACCINE AGAINST COYPU SALMONELLOSIS | 2005 |
|
RU2279891C1 |
| POLYVALENT INACTIVATED VACCINE AGAINST RIEMERELLOSIS, PASTEURELLOSIS AND SALMONELLOSIS OF TURKEYS, DUCKS AND GEESE, THE METHOD OF ITS PREPARATION | 2020 |
|
RU2750865C1 |
| METHOD FOR MANUFACTURING ASSOCIATED VACCIONE AGAINST COLIBACTERIOSIS, SALMONELLOSIS, STREPTOCOCCOSIS AND ENTEROCOCCAL INFECTION IN NUTRIAS | 2006 |
|
RU2316345C1 |
| METHOD FOR PREPARING ASSOCIATED VACCINE AGINST SALMONELLOSIS AND COLIBACTERIOSIS IN NUTRIAS | 2005 |
|
RU2292915C1 |
| METHOD FOR PREPARING MIXED VACCINE AGAINST COLI-BACTERIOSIS, SALMONELLOSIS AND STREPTOCOCCOSIS IN NUTRIA | 2006 |
|
RU2301077C1 |
| METHOD OF MANUFACTURING OF VACCINE ASSOCIATED AGAINST COLIBACILLOSIS, SALMONELLOSIS AND ENTEROCOCCUS INFECTIONS OF NUTRIAS | 2006 |
|
RU2338554C2 |
| METHOD FOR PREPARING ASSOCIATED VACCINE AGINST SALMONELLOSIS AND ENTEROCOCCAL INFECTION IN NUTRIAS | 2005 |
|
RU2292914C1 |
| METHOD FOR PREPARING ASSOCIATED VACCINE AGINST SALMONELLOSIS AND STREPTOCOCCOSIS IN NUTRIAS | 2005 |
|
RU2292911C1 |
| METHOD FOR PRODUCING ASSOCIATED SALMONELLOSIS, ESCHERICHIOSIS AND RABBIT VIRAL HEMORRHAGIC DISEASE VACCINE | 2012 |
|
RU2496518C1 |
| MIXED INACTIVATED VACCINE FOR CONTROL OF CHLAMYDIOSIS, CAMPYLOBACTERIOSIS, SALMONELLOSIS AND LEPTOSPIROSIS IN SHEEP AND GOATS | 1994 |
|
RU2086259C1 |
