METHOD FOR PRODUCTION OF VACCINE AGAINST COYPU SALMONELLOSIS Russian patent published in 2006 - IPC A61K39/112 

Abstract RU 2279891 C1

FIELD: veterinary medicine.

SUBSTANCE: claimed method includes sampling of pathological material from fallen coypu from local epizootic focus and preparation of suspension therefrom. Suspension is seeded on differential diagnostic media, and pure culture of salmonella typhimurium is isolated. Pure culture is cultivated in liquid broth with addition of 0.2 % of glucose to produce microbial cell concentration of 4-5x109 per 1 cm3. Culture is inactivated with formalin up to finish concentration of 0.4-0.6 % and conditioned at 37°C for 82-96 hours. Then 3 % solution of aluminum hydroxide is introduced in amount of 15 % based on culture volume, mixture is thoroughly agitated, pre-packed and sealed.

EFFECT: specific vaccine of high immunogenic properties.

1 tbl, 1 ex

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RU 2 279 891 C1

Authors

Shevchenko Aleksandr Alekseevich

Shevchenko Ljudmila Vasil'Evna

Shantyz Alij Jusupovich

Pak Nadezhda Evgen'Evna

Dates

2006-07-20Published

2005-02-08Filed