FIELD: organic chemistry, in particular stereoselective method for production of dihydroxyesters and derivatives thereof.
SUBSTANCE: disclosed is method for production of compound having formula 
1, wherein R and R' represent optionally substituted hydrocarbon groups; X represents hydrocarbon linker group. Claimed method includes either stereoselective ketogroup reducing to dihydroketo precursor followed by selective etherification of primary hydroxyl or selective etherification of primary dihydroketo precursor hydroxyl followed by stereoselective ketogroup reducing.
EFFECT: compounds useful in production of pharmaceutical compositions.
19 cl, 1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIHYPERTRIGLYCERIDEMIC COMPOSITION (VARIANTS), METHOD OF ITS PREPARING, METHOD OF TREATMENT OR PROPHYLAXIS OF HYPERTRIGLYCERIDEMIA | 1995 |
|
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| METHOD FOR ORGANIC COMPOUNDS PREPARATION | 2003 |
|
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| METHOD OF PRODUCING DIARYL CYCLOALKYL DERIVATIVES | 2005 |
|
RU2414459C2 |
| OBTAINING (3aS, 7aR)-HEXAHYDROISOBENZOFURAN-1(3H)-ONE BY CATALYTIC BIOLOGICAL CLEAVAGE OF DIMETHYLCYCLOHEXANE-1,2-DICARBOXYLATE | 2011 |
|
RU2570635C2 |
| COMBINATION CONTAINING A COMPOUND OF ANGIOTENSIN II-ANTAGONISTIC ACTIVITY | 1997 |
|
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| METHODS OF PRODUCING (CYCLOPENTYL[D]PYRIMIDIN-4-YL)PIPERAZINE COMPOUNDS | 2015 |
|
RU2732404C2 |
| METHODS OF PRODUCING (CYCLOPENTYL[D]PYRIMIDIN-4-YL)PIPERAZINE COMPOUNDS | 2015 |
|
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| FLUORINE-SUBSTITUTED (3R,4R,5S)-5-GUANIDINO-4-ACYLAMINO-3-(PENTAN-3-YLOXY)CYCLOHEXENE-1-CARBOXYLIC ACIDS, ESTERS THEREOF AND METHOD OF APPLICATION | 2012 |
|
RU2489422C1 |
| CONDENSED HETEROCYCLIC COMPOUNDS AND SQUALENE-SYNTHETASE INHIBITORS | 1994 |
|
RU2129547C1 |
| EGFR INHIBITOR | 2021 |
|
RU2817044C1 |
