FIELD: medicine, traumatology, orthopedics, stomatology, neurosurgery.
SUBSTANCE: invention relates to material designated for replacing defects in different osseous pathologies. Material for replacing osseous tissue defects represents plates consisting of fluorohydroxyapatite in collagen wherein the content of fluorohydroxyapatite is 40-90% by mass. Method for preparing of material involves placing a porous collagen matrix between solutions containing calcium chloride in the concentration 0.2-1 mole/l and solution containing sodium phosphate or ammonium phosphate in the concentration 0.1-1 mole/l and ammonium fluoride in the concentration 0.01-1 mole/l and ammonium or sodium hydroxide solution. Electrophoresis is carried out at current density 7-20 mA/cm2 for 10-24 h, prepared material is washed out with distilled water, dried at 20-37°C and sterilized.
EFFECT: improved preparing method, valuable medicinal properties of material.
3 cl, 2 tbl, 1 ex
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Authors
Dates
2006-04-20—Published
2004-02-26—Filed