OXADIAZOLE DERIVATIVES POSSESSING ANTI-TUMOR EFFECT, MEDICINAL AGENT COMPRISING THEREOF AND METHOD FOR TREATMENT Russian patent published in 2006 - IPC C07D413/12 C07D413/14 A61K31/4245 A61P35/00 A61P35/04 

Abstract RU 2275371 C2

FIELD: organic chemistry, medicine, oncology, pharmacy.

SUBSTANCE: invention relates to new sulfonamide derivatives possessing anti-tumor activity, namely to compounds of the formula (I): wherein R6 means hydroxyl; R7 means methyl, isopropyl, isobutyl, benzyl or indole-3-ylmethyl; R8 means hydrogen atom; R9 means phenylene; R10 means thienyl, furyl or pyridyl optionally substituted with lower alkyl or halogen atom. Also, invention relates to their derivatives or pharmaceutically acceptable salts or solvates. Invention describes medicinal agents used in treatment or prophylaxis of cancer and for prophylaxis of metastasis. Also, invention describes a case for treatment of cancer in mammal.

EFFECT: improved treatment method, valuable medicinal properties of agent.

5 cl, 17 tbl, 112 ex

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RU 2 275 371 C2

Authors

Eshioka Takajuki

Maekava Rjuji

Vatanabe Fumikhiko

Dates

2006-04-27Published

2001-04-16Filed