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2 276 149

(13)

(51)

IPC

C07D317/28(2006-01-01)

A61K31/495(2006-01-01)

A61P11/00(2006-01-01)

(21) (22)

Application

2003105691/04, 2001-07-18

(24)

Start date

2001-07-18

(22)

Actual filing date

2001-07-18

(45)

Published

2006-05-10

(72)

Inventor

Allegretti MarchelloChesta Marija KandidaKurti RobertoPellegrini LuidzhiMelillo Gabriella

(73)

Holder

Dompe` S.P.A.

1,3-DIOXOLANES, METHOD FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION Russian patent published in 2006 - IPC C07D317/28 A61K31/495 A61P11/00

Abstract RU 2276149 C2

FIELD: organic chemistry, chemical technology, medicine, pharmacy.

SUBSTANCE: invention relates to new 1,3-dioxolanes of the formula (1): wherein each Ra and Rb can be similar or different and represents hydrogen atom or (C₁-C)-alkyl; or Ra and Rb in common with carbon atom C to which they are joined form optionally substituted 4-7-membered carbocyclic ring. Also, invention relates to a method for preparing compounds of the formula (1) and a pharmaceutical composition based on thereof possessing ant-coughing activity. Invention provides preparing new compounds possessing the valuable pharmacological effect.

EFFECT: improved preparing method, valuable medicinal property of compounds and pharmaceutical composition.

8 cl, 8 ex

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RU 2 276 149 C2

Authors

Allegretti Marchello

Chesta Marija Kandida

Kurti Roberto

Pellegrini Luidzhi

Melillo Gabriella

Dates

2006-05-10—Published

2001-07-18—Filed