PERFLUOROALKYL-CONTAINING COMPLEXES WITH SUGAR RESIDUES, METHODS FOR THEIR PREPARING Russian patent published in 2006 - IPC C07D257/02 C07D295/22 A61K49/04 A61K49/06 A61K49/10 

FIELD: organic chemistry, chemical technology, medicine.

SUBSTANCE: invention describes perfluoroalkyl-containing complexes with residues of sugars of the general formula (I): wherein R means mono- or oligosaccharide residue added through 1-OH- or 1-SH-position; R_f means perfluorinated carbon chain; K means the metal complex of the formula (II) wherein R¹ means hydrogen atom (H) or equivalent of metal ion with order number 21-29 or 58-71 under condition that at least two radicals of R¹ represent metal ions; R² and R³ mean independently hydrogen atom (H), (C₁-C₆)-alkyl, benzyl, phenyl; U means the group C₆H₄-O-CH₂-ω- or (C₂-C₈)-alkylene, or (C₆-C₉-C₆H₄-O-group optionally broken with one oxygen atom (O), 1,2-NHCO-groups or 1,2-CONH-group wherein ω means a point of addition to -CO-; Y and Z represent linker-groups useful for using in intravenous lymphography, tumor diagnosis and for visualization of infarctions and necrosis.

EFFECT: valuable medicinal properties of complexes.

11 cl, 1 tbl, 2 dwg, 39 ex