PERFLUOROALKYL-CONTAINING COMPLEXES WITH POLAR RESIDUES, METHOD FOR THEIR PREPARING, PHARMACEUTICAL AGENT Russian patent published in 2006 - IPC C07D257/12 C07D295/22 A61K49/04 A61K49/06 A61K49/10 C07D405/14 

Abstract RU 2289579 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention describes perfluoroalkyl-containing complexes with polar residues of the general formula (I):

wherein R means a polar residue; G means a trifunctional residue, a perfluorinated carbon chain; K means a metal complex; Z means a linker group. Proposed complexes can be used for intravenous lymphography, tumor diagnosis and for visualization of infarctions and necrosis. Also, invention describes a method for synthesis of these complexes.

EFFECT: valuable medicinal properties of complexes.

16 cl, 1 tbl, 26 ex

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RU 2 289 579 C2

Authors

Plattsek Iogannes

Mareski Peter

Nidballa Ul'Rikh

Radjukhel' Bernd

Vajnmann Khanns-Joakhim

Missel'Vitts Bernd

Dates

2006-12-20Published

2001-07-23Filed