FIELD: biotechnology, in particular antibiotic production and new erythromycin producer.
SUBSTANCE: claimed strain is obtained by mutant selection from S.erythraea strain. Said strain is characterized with high specific rate of antibiotic formation (120±10 mg of erythromycin/g of dry biomass/h). Level of erythromycin formation after seven days of culturing in discontinuous process is 8250 mug/ml. Strain of present invention makes it possible to increase by 10 % level of erythromycin formation in contrast to starting strain and to decrease by 15-20 % formed biomass amount. Maximum synthesis specific rate is by 30 % higher in contrast to starting strain.
EFFECT: strain for accelerated synthesis of antibiotic erythromycin.
1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| STRAIN SACCHAROPOLYSPORA ERYTHRAEA 52 - PRODUCER OF ANTIBIOTIC ERYTHROMYCIN | 1999 |
|
RU2142509C1 |
| STRAIN STREPTOMYCES CINNAMOMENSIS AC-1638 - PRODUCER OF MONENSIN A | 2002 |
|
RU2241755C2 |
| STRAIN STREPTOMYCES FRADIAE - A PRODUCER OF TYLOSIN | 1994 |
|
RU2065878C1 |
| STRAIN STREPTOMYCES BAMBERGIENSIS - A PRODUCER OF MOENOMYCIN A | 1992 |
|
RU2013448C1 |
| STRAIN STREPTOMYCES RIMOSUS SOBIN, FINALLY AND KANE - A PRODUCER OF OXYTETRACYCLINE | 1993 |
|
RU2061044C1 |
| STRAIN AND BIOSYNTHESIS METHOD OF PRODUCING ANTIBIOTIC MITOMYCIN | 2009 |
|
RU2420568C2 |
| METHOD OF PRODUCING ANTIBIOTIC ACTINOPLACIN, STRAIN STREPTOMYCES (KITASATOA) SPECIES 834 VNIISKHM D-484 AS PRODUCER OF ANTIBIOTIC ACTINOPLACIN | 1997 |
|
RU2151793C1 |
| STRAIN STREPTOMYCES FRADIALE AS PRODUCT OF TYLOSIN | 1992 |
|
RU2018536C1 |
| ACTINOMYCES GRISEUS-R-42-110 STRAIN AS CORNOGRISIN PRODUCENT | 0 |
|
SU734271A1 |
| METHOD OF AVERMECTIN PREPARING, STRAIN STREPTOMYCES AVERMITILIS - A PRODUCER OF AVERMECTIN | 1995 |
|
RU2098483C1 |
