FIELD: medicine, hematology.
SUBSTANCE: it is necessary to isolate DNA out of lymphocytes of peripheral venous blood due to phenolic-chloroform extraction followed by genotyping polymorphism C3435T of promoter area of multidrug resistance gene MDR 1 due to polymerase chain reaction of DNA synthesis with subsequent restriction. At detecting genotype CT in a patient one should predict favorable flow of the disease due to the absence of toxic lesion of inner organs.
EFFECT: higher accuracy of prediction.
2 ex, 1 tbl
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