FIELD: medicine.
SUBSTANCE: what is presented is a method for prediction of the form of non-Hodgkin lymphomas involving the DNA recovery from peripheral venous blood lymphocytes, PCR and restriction of the amplification products. That is followed by genetic typing of the polymorphous locus -248G>A of Bc1-2 gene of the associated X protein (BAX -248G>A). If observing the genotype GG in the patient, a high probability of the B cell form of non-Hodgkin lymphomas is predicted, the genotype GA or the allele A show a high probability of the T cell form of non-Hodgkin lymphomas.
EFFECT: more accurate prediction of the form of non-Hodgkin lymphomas if the histological aspect of the disease appears to be uncertain.
1 tbl, 3 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR PREDICTION OF CLINICAL COURSE OF NON-HODGKIN LYMPHOMAS | 2012 |
|
RU2490641C1 |
METHOD FOR PREDICTION OF SMOULDERING FORM OF CHRONIC LYMPHOLEUKAEMIA | 2012 |
|
RU2496110C1 |
METHOD FOR PREDICTION OF CLINICAL FORM OF CHRONIC LYMPHOLEUKAEMIA | 2012 |
|
RU2490642C1 |
METHOD FOR PREDICTING THE DEVELOPMENT AND FLOW OF CHRONIC LYMPHOLEUKOSIS | 2003 |
|
RU2248574C1 |
METHOD FOR PROGNOSIS OF MULTIPLE MYEOLOMA COURSE | 2002 |
|
RU2225612C2 |
METHOD FOR PREDICTION CHEMOTHERAPEUTIC RESPONSE IN CHRONIC LYMPHATIC LEUKAEMIA | 2012 |
|
RU2495427C1 |
METHOD FOR PREDICTING THE DEVELOPMENT OF TOXIC HEPATITIS AT CHEMOTHERAPY OF MULTIPLE MYELOMA | 2005 |
|
RU2283494C1 |
METHOD FOR PREDICTING THE FLOW OF MULTIPLE MYELOMA | 2005 |
|
RU2282852C1 |
METHOD FOR PREDICTION OF SEVERITY OF CLINICAL COURSE OF ACUTE PYOINFLAMMATORY DISEASES OF MAXILLOFACIAL AREA IN CHILDREN | 2012 |
|
RU2483307C1 |
METHOD FOR PREDICTING THE DEVELOPMENT OF CHILDHOOD OBESITY IN THE REPUBLIC OF BASHKORTOSTAN | 2022 |
|
RU2794991C1 |
Authors
Dates
2013-08-20—Published
2012-08-01—Filed