FIELD: medicine.
SUBSTANCE: method involves separating DNA from peripheral venous blood leukocytes using DNA synthesis polymerase chain reaction method, class II DQB1 HLA gene specificity amplification method. When detecting DQB1*0302/07/08 allele and DQB1*02/DQB1*03 genotype in Bashkirian people and DQB1*0302/08 allele in Russian people, DQB1*02 specificity and DQB1*0302/08 allele in Tatar people, type 1 diabetes mellitus risk is predicted to take place.
EFFECT: high accuracy of prognosis.
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Authors
Dates
2006-10-20—Published
2005-02-08—Filed