FIELD: medicine.
SUBSTANCE: the present innovation deals with isolating DNA out of lymphocytes of peripheral venous blood due to polymerase chain reaction technique, synthesis of DNA amplification of genes PON1 and CETP fragments within the limits of which polymorphous nucleotide substitutions are localized, carrying out the analysis of polymorphism in the lengths of restriction fragments of amplicons and at detecting genotypes PON*BB and CETP*II one should predict the risk in development of hypertonic disease.
EFFECT: higher accuracy of prediction.
4 ex, 4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTION OF RISK OF HYPERTENSION IN MALES | 2011 |
|
RU2456608C1 |
| METHOD FOR PREDICTION OF RISK OF ESSENTIAL HYPERTENSION DEVELOPMENT BASED ON MATRIX METAL PROTEINASE GENES COMBINATIONS | 2016 |
|
RU2624480C1 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING ESSENTIAL HYPERTENSION IN WOMEN | 2011 |
|
RU2458144C1 |
| METHOD FOR PREDICTING THE DEVELOPMENT OF TOXIC HEPATITIS AT CHEMOTHERAPY OF MULTIPLE MYELOMA | 2005 |
|
RU2283494C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPING ESSENTIAL HYPERTENSION | 2017 |
|
RU2661604C1 |
| METHOD FOR ASSESSING GENETIC RISK OF ATHEROSCLEROSIS BASED ON DETERMINATION OF MITOCHONDRIAL GENOME VERSIONS | 2015 |
|
RU2592233C1 |
| METHOD FOR PREDICTION OF BLOOD PRESSURE LEVEL IN PREGNANT WOMEN DEPENDING ON GENETIC ENDOTHELIN 1 POLYMORPHISM | 2011 |
|
RU2473912C1 |
| METHOD OF PREDICTING THE RISK OF DEVELOPING HYPERTENSION IN INDIVIDUALS WHO HAVE FAMILY HISTORY | 2014 |
|
RU2580310C1 |
| METHOD FOR DETECTING GENETIC PREDISPOSITION TO RECURRENT PREGNANCY LOSS | 2012 |
|
RU2532367C2 |
| METHOD FOR PREDICTING RISK OF DEVELOPMENT OF HYPERTENSIVE DISEASE FACTORED IN GENETIC AND ENVIRONMENTAL FACTORS | 2018 |
|
RU2678441C1 |
