FIELD: medicine.
SUBSTANCE: invention relates to medicine and is intended to predict the risk of developing essential hypertension. In individuals of Russian nationality, who are residents of the Central Chernozem Region, perform DNA isolation from peripheral venous blood and analyze genetic markers of matrix metalloproteinases. High risk of developing essential hypertension is predicted when observing a combination of the genotype TT rs11225395 MMP-8, genotype GG rs17577 MMP-9 and the positive status of smoking.
EFFECT: invention provides new criteria for assessing the risk of developing essential hypertension in individuals of Russian nationality, natives of the Central Chernozem region.
1 cl, 3 dwg, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTING RISK OF DEVELOPING ESSENTIAL HYPERTENSION IN WOMEN BASED ON GENETIC FACTORS | 2017 |
|
RU2664428C1 |
| METHOD FOR PREDICTING THE RISK OF STROKE IN MEN BASED ON GENETIC TESTING | 2017 |
|
RU2664430C1 |
| METHOD FOR PREDICTION OF RISK OF ESSENTIAL HYPERTENSION DEVELOPMENT BASED ON MATRIX METAL PROTEINASE GENES COMBINATIONS | 2016 |
|
RU2624480C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPING AN ISCHEMIC STROKE, TAKING INTO ACCOUNT GENETIC FACTORS | 2017 |
|
RU2653450C1 |
| METHOD FOR PREDICTING RISK OF DEVELOPMENT OF HYPERTENSIVE DISEASE FACTORED IN GENETIC AND ENVIRONMENTAL FACTORS | 2018 |
|
RU2678441C1 |
| METHOD FOR PREDICTION OF SEVERE PREECLAMPSIA DEVELOPMENT RISK CONSIDERING GENETIC DATA | 2017 |
|
RU2653765C1 |
| METHOD FOR PREDICTION OF RISK OF PREECLAMPSIA DEVELOPMENT BASED ON MATRIX METAL PROTEINASE GENES COMBINATIONS | 2017 |
|
RU2646448C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPING HYPERTENSIVE DISORDER BASED ON MOLECULAR AND GENETIC DATA | 2018 |
|
RU2679401C1 |
| METHOD FOR PREDICTING RISK OF DEVELOPING PRIMARY OPEN-ANGLE GLAUCOMA IN WOMEN ACCORDING TO GENETIC DATA | 2021 |
|
RU2753270C1 |
| METHOD FOR PREDICTION OF RISK OF PREECLAMPSIA DEVELOPMENT IN WOMEN DEPENDING ON HEREDITARY BURDEN | 2016 |
|
RU2646455C1 |
