GEL COMPOSITION FOR TREATMENT OF STOMATOLOGICAL DISEASE AND METHOD FOR ITS PREPARING Russian patent published in 2006 - IPC A61K8/99 A61K8/97 A61K8/73 A61K8/43 A61K8/36 A61K8/34 A61Q11/00 

FIELD: medicine, stomatology.

SUBSTANCE: invention relates to a gel composition used in treatment of stomatological diseases. The composition comprises an active component represented by diclofenac and chlorhexidine gluconate, mucoadhesive reagent, gel-forming agent and a pharmaceutically acceptable excipient wherein components are taken in the definite ratio. The composition is prepared by dissolving diclofenac in propylene glycol followed by addition of carboxyvinyl polymer and copolymer of methylvinyl ester with maleic anhydride and the following addition of prepared solution to a separately prepared system of solvents at continuous stirring, the following addition to the prepared gel of EDTA disodium salt aqueous solution, saccharin sodium salt and chlorhexidine gluconate up to the complete dissolution. Prepared composition provides retaining a medicinal preparation on the damaged site for the more long time and provides local delivery of the preparation for therapeutic effect.

EFFECT: improved preparing method, valuable medicinal properties of gel composition.

21 cl, 3 tbl, 3 ex