METHOD FOR DETERMINING RADIONUCLIDE ESTIMATION OF REPARATIVE OSTEOGENESIS Russian patent published in 2007 - IPC A61K49/04 A61B6/00 

FIELD: medicine.

SUBSTANCE: method involves carrying out polyphase scintigraphy with osteotropic radiopharmaceutical preparation RPP and comparing RPP accumulation in tibia to a reference value. RPP accumulation level in tibia is determined from local bone fraction of RPP accumulation using formula LBFA_RPP = A*K/((S_pre- S_post)*5), where LBFA_RPP is the local bone fraction of RPP accumulation, A is the scintillation count in region under study within 5 min, K is the initial ^99mTc radionuclide activity change coefficient beginning from the RPP introduction moment, S_pre is the preinjection scintillation count of RPP syringe within 1 min, S_post is the postinjection scintillation count of RPP syringe within 1 min, 5 is adjustment coefficient for determining scintillation count time. LBFA_RPP being >0.50-0.67% in upper tibia one-third, LBFA_RPP being >0.25-0.31% in middle tibia one-third, LBFA_RPP being >0.23-0.35% in lower tibia one-third, increased reparative osteogenesis process intensity is to be determined.

EFFECT: high accuracy of estimates.

4 dwg, 4 tbl