P-A-SUP35MC HYBRID GENE FOR ANALYSIS OF FACTORS REGULATING PRODUCTION, AGGREGATION AND DISAGGREGATION OF HUMAN AMYLOID β (A) PEPTIDE IN YEAST SYSTEM Russian patent published in 2007 - IPC C12N15/62 

Abstract RU 2294964 C2

FIELD: biotechnology, medicine.

SUBSTANCE: Pcup1-Aβ-SUS35MC hybrid gene is produced on the base of CUP1 promoter, sequence encoding of full-length human amyloid beta (Aβ) peptide, sequence encoding of M and C domains of Sup35 protein of Saccharomyces cerevisiae, and translation terminating sequence.

EFFECT: method for scale screening of Aβ-peptide aggregation regulating agents.

2 dwg

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RU 2 294 964 C2

Authors

Galkin Aleksej Petrovich

Tsaponina Ol'Ga Evgen'Evna

Rubel' Aleksandr Anatol'Evich

Navolotskaja Viktorija Vasil'Evna

Lada Artem Gennadievich

Petrova Irina Tomasovna

Smirnov Aleksandr Fedorovich

Inge-Vechtomov Sergej Georgievich

Dates

2007-03-10Published

2004-11-03Filed