METHOD FOR FINDING LIGANDS Russian patent published in 2007 - IPC C07C321/12 C40B20/00 C40B30/00 C07B61/00 

Abstract RU 2295518 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to a conjugate target - compound chosen from the following group: and wherein means a target; each among R and R' means independently unsubstituted (C1-C20)-aliphatic group, substituted (C1-C20)-aliphatic group, unsubstituted aryl or substituted aryl wherein aryl is a radical chosen from the group comprising phenyl, naphthyl, tetrahydronaphthyl, indanyl, indenyl, pyridyl, pyrazinyl, pyrimidinyl, pyrrolyl, pyrazolyl, imidazolyl, thiazolyl, oxazolyl, isooxazolyl, thiadiazolyl, oxadiazolyl, thiophenyl, furanyl, quinolinyl, isoquinolinyl; m = 0, 1 or 2; n = 1 or 2. Also, invention describes library of compounds, method for identifying compounds, method for identifying the potential ligand. Proposed invention can promote to discovery of medicinal preparations.

EFFECT: valuable method for finding ligands.

20 cl, 8 dwg, 4 tbl, 21 ex

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RU 2 295 518 C2

Authors

Ehrlanson Daniel A.

Brajsted Ehndr'Ju S.

Uehlls Dzhejms

Dates

2007-03-20Published

2002-04-24Filed