FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention relates to 3-piperidinoethylphenylketones of the general formula (I): wherein R means nondeuterated, mono- or multi-deuterated or perdeuterated alkyl comprising up to 3 carbon atoms; all radicals R' represent hydrogen atom, or all represent deuterium; radicals R'' represent independently of one another deuterium or hydrogen atom wherein at least one of radicals R, R' or R'' represents deuterium or comprises deuterium, and to their physiologically tolerant salts. Compounds of the formula (I) and their salts can be used in treatment of diseases associated with symptoms in muscular region, such as morbid reflex-muscular tensions of skeletal musculature and/or nervous-muscular convulsions.
EFFECT: valuable medicinal properties of compounds and pharmaceutical composition.
5 cl, 5 dwg, 10 ex
Title | Year | Author | Number |
---|---|---|---|
DEUTERATED DEFACTINIB COMPOUNDS AND THEIR APPLICATION | 2019 |
|
RU2761825C1 |
DEUTERATED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS IMAGING MEANS | 2015 |
|
RU2696492C2 |
DEUTERATED HETEROCYCLIC COMPOUNDS AND THEIR USE AS IMAGING TOOLS | 2015 |
|
RU2791900C1 |
FAK INHIBITOR AND DRUG COMBINATIONS THEREWITH | 2019 |
|
RU2820555C2 |
DEUTERATED HEPATITIS C PROTEASE INHIBITORS | 2007 |
|
RU2465264C2 |
DYETERED DIAMINOPYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH CONNECTIONS | 2014 |
|
RU2632907C2 |
PAROXETINE DERIVATIVE | 2013 |
|
RU2616610C2 |
HALOGEN-SUBSTITUTED PHENYLATE COMPOUND AND USE THEREOF | 2020 |
|
RU2820475C2 |
INHIBITOR CONTAINING BICYCLIC DERIVATIVE, METHOD OF PREPARATION AND USE THEREOF | 2020 |
|
RU2820948C2 |
METHOD OF TREATMENT OR PREVENTION OF PHYSIOLOGICAL AND/OR PATHOPHYSIOLOGICAL CONDITIONS MEDIATED BY GROWTH HORMONE SECRETION STIMULATING RECEPTORS, TRIAZOLE AND BASED PHARMACEUTICAL COMPOSITION | 2006 |
|
RU2415134C9 |
Authors
Dates
2007-04-10—Published
2002-04-29—Filed