FIELD: organic chemistry, biology, pharmacy.
SUBSTANCE: invention relates to derivatives of thieno[2,3-d]pyrimidine of the general formula (I): 
or their pharmaceutically acceptable salts wherein R1 and R2 in common with nitrogen atom to which they are added form a ring comprising from 2 to 6 carbon atoms and optionally comprising one or more heteroatoms chosen from nitrogen (N), oxygen (O) and/or sulfur (S) atoms. Proposed compounds possess ability to activate both luteinizing hormone (LH) and follicle-stimulating hormone (FSH) and can be used in therapy in aims for regulating fertility. Also, invention describes a pharmaceutical composition based on compounds of the formula (I).
EFFECT: valuable biological and medicinal properties of compounds and pharmaceutical composition.
6 cl, 1 tbl, 7 ex
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|---|---|---|---|
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