THERAPEUTIC COMPOUNDS AND COMPOSITIONS AND METHODS OF USING THEM Russian patent published in 2022 - IPC C07D487/04 A61K31/519 A61P29/00

Abstract RU 2769696 C2

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention relates to pyrazolopyrimidine derivatives or a stereoisomer thereof selected from the group consisting of following compounds 1–18:

Invention also relates to a pharmaceutical composition having Janus kinase 1 (JAK1) inhibitory activity based on said compounds.

EFFECT: obtaining novel compounds and a pharmaceutical composition based on said compounds, which can be used in medicine for treating a disease or a condition responding to inhibition of Janus kinase activity.

23 cl, 2 tbl, 18 ex

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RU 2 769 696 C2

Authors

Zak, Mark

Romero, F. Entoni

Chen, Yun-Sin

Dates

2022-04-05—Published

2018-05-21—Filed