METHODS FOR MEASUREMENT OF DISSOLVING RATE OF ANALYZED SUBSTANCE IN NONAQUEOUS LIQUID COMPOSITION Russian patent published in 2007 - IPC G01N33/15 

Abstract RU 2300766 C2

FIELD: analytical measurements, pharmacy.

SUBSTANCE: method involves using a substance representing a pharmaceutically active component in a medicinal formulation characterized by sustained releasing preferably. Method involves carrying out the following procedures: (1) contacting a diluted nonaqueous composition containing analyzed substance and nonaqueous base, for example, wax or fat with an aqueous dissolving medium for predetermined time, and (ii) measurement of analyzed substance amount in aqueous dissolving medium. Invention provides enhancing precision and safety in assay of dissolving rate of analyzed substance.

EFFECT: improved assay method.

34 cl, 8 dwg, 3 tbl

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RU 2 300 766 C2

Authors

Shapof Rehndal Li

Tsiolkovski Ehdvard L.

Iton Lesli K.

Dates

2007-06-10Published

2003-09-10Filed