ANALOGS OF VITAMIN D Russian patent published in 2007 - IPC C07C33/26 C07C43/23 C07C215/68 A61K8/34 A61K8/41 A61K8/33 A61K31/85 A61K31/137 A61K31/47 A61P3/02 A61P3/10 A61P17/00 A61P19/08 A61P37/00 

Abstract RU 2301794 C2

FIELD: organic chemistry, vitamins.

SUBSTANCE: invention relates to novel triaromatic compounds, namely, analogs of vitamin D of the general formula (I): wherein values R1, R2, R3, X and Y are given in claim 1 of the invention claim. Also, invention relates to using these compounds in pharmaceutical compositions designated for treatment of the following diseases: (1) dermatological diseases associated with differentiation disturbance or proliferation of keratinocytes or sebocytes; (2) keratinization disorders; (3) dermatological diseases associated with disturbance of keratinization with inflammatory and/or immunoallergic components; (4) inflammatory diseases that don't represent keratinization disturbance; (5) cutaneous or epidermic expansion; (6) dermatological disorders, for example, vesicle dermatosis and collagenosis; (7) photoinduced or senile skin ageing, or for decreasing photoinduced pigmentations and keratosis, or any other pathologies associated with senile or photoinduced ageing; (8) skin healing and scar disturbances; (9) lipid function disturbances, such as acne hypersteatosis, simple seborrhea or seborrheic eczema; (10) dermatological diseases with immunologic component. Also, invention relates to cosmetic using the cosmetic composition for body and hair hygiene.

EFFECT: valuable medicinal and cosmetic properties of compounds.

16 cl, 3 tbl, 7 dwg, 10 ex

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RU 2 301 794 C2

Authors

Bernardon Zhan-Mishel'

B'Jadatti Tibo

Dates

2007-06-27Published

2002-12-06Filed