INDOLYL DERIVATIVES AS LIVER X-RECEPTOR MODULATORS Russian patent published in 2009 - IPC C07D413/06 C07D209/12 C07D209/08 A61K31/404 C07D209/30 C07D413/10 C07D401/06 A61P3/06 C07D403/06 C07D409/06 C07D417/06 

Abstract RU 2368612 C2

FIELD: chemistry.

SUBSTANCE: invention relates to formula (I) compounds and to their use in treating diseases related to lipid storage disorders, such as atherosclerosis and diabetes. In R1 represents hydrogen, alkyl, halogen, formyl, hydroxyalkyl or trifluoromethyl, R2 represents hydrogen, alkyl or halogen, R3 represents hydrogen or alkyl, R4 represents hydrogen, alkyl, hydroxy or alkoxy, R5 and R6 are chosen from hydrogen, alkyl, phenylalkyl, hydroxyalkyl, alkoxycarbonyl and phenyl, A represents aryl or heterocyclyl, m equals 0-3, n equals 0-1, p equals 0-3, sum of m, n and p equals 1-4, the bond between carbon atoms Ca and Cb is a single or double carbon-carbon bond.

EFFECT: obtaining new biologically active compounds.

27 cl, 147 ex

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RU 2 368 612 C2

Authors

Demlov Genrietta

Kun Bernd

Pandaj Narendra

Ratni Khasane

Shul'Ts-Gash Tanja

Rajt Matt'Ju Blejk

Dates

2009-09-27Published

2005-04-26Filed